Many reports confirmed excellent biocompatibility and ability of bony regeneration of e-PTEE (Gore-tex membrane) in the Oral & maxillofacial field. At present, the term「Guided bone regeneration」and osteopromotion are mainly used in the
literature
for
this membrane technique. Biologically membrane coverage of bone defects create a suitable environment for bone regeneration. However, disadvantages of high cost and necessity of membrane removal still remained. Recently, biodegradable membranes
have
been studied and used
The present study was designed to consider the effect of lyodura and microfilter for replacement of Gore-tex membrane in rat's osseous defects. The experimental groups were divided into 2 groups. Group 1 is the lyodura group, Group 2 is the
microfilter
group. The control group was the contralateral angle defect without membrane coverage. Fullthickness bony defects to expose the marrow 8×8 mm in size were created in the right and left mandible angle of rats, and then lyodura and microfilter
were
covered on the left side and not covered in the right side as a control. Each group was sacrificed after 1 week, 3 weeks, 5 weeks, and 8 weeks after surgery and histologic examination was performed.
Both experimental groups had earlier and more bone formation than the control group. The Lyodura group seemed to have more bone formation than the Microfilter group. These results suggest that Lyodura may be very useful in GTR for replacement of
Gore-tex material.
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